Behandlung von Opioidsucht - Eine Übersicht
Behandlung von Opioidsucht - Eine Übersicht
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Methadone is contraindicated in patients with a known hypersensitivity to methadone hydrochloride or any other ingredient hinein methadone hydrochloride tablets.
The use of methadone in patients already known to have a prolonged QT interval has not been systematically studied.
Don’t put this medication rein your car’s glove compartment or leave it rein the car. Beryllium sure to avoid doing this when the weather is very hot or very cold.
In patients being treated for opioid dependence, this should include weighing the risk of methadone against the risk of maternal illicit drug use.
Sowie geklärt ist, wie es bei einem Patienten nach dem besagten Opioidmissbrauch gekommen ist ebenso der Patient sogar griffbereit ist, zigeunern behandeln zu lassen, kann die weitere Handlungsweise besprochen werden.
The physician should not confuse such symptoms with those of narcotic abstinence and should not attempt to treat anxiety by increasing the dose of methadone. The action of methadone hinein maintenance treatment is limited to the control of narcotic withdrawal symptoms and is ineffective for relief of general anxiety.
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Methadone is a mu-agonist opioid with an abuse liability similar to that of morphine and is a Schedule II controlled substance. Methadone, like morphine and other opioids used for analgesia, has the potential for being abused and is subject to criminal diversion.
Abrupt opioid discontinuation can lead to development of opioid withdrawal symptoms (see PRECAUTIONS). Presentation of these symptoms have been associated with an increased risk of susceptible patients to relapse to illicit drug use and should Beryllium considered when assessing the risks and benefit of methadone use.
Proper assessment of the patient, proper prescribing practices, periodic Response-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.
The rate at which methadone is decreased should be determined separately for each patient. The dose of methadone can be decreased on a daily Stützpunkt or at 2-day intervals, but the amount of intake should remain sufficient to keep withdrawal symptoms at a tolerable level. Hinein hospitalized patients, a daily reduction of 20% of the total daily dose may Beryllium tolerated. In ambulatory patients, a somewhat slower schedule may Beryllium needed.
Examples of benzodiazepines include lorazepam, clonazepam, and alprazolam. These drugs should only be used with methadone when other drugs don’t work well enough.
Clinical studies of methadone did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently compared to younger subjects. Other reported clinical experience has not identified differences hinein responses between elderly and younger patients.
Initial doses should not be determined by previous treatment episodes or dollars spent mit hilfe day on illicit drug use.